Cynk-001 clinical trial
WebJan 22, 2024 · The clinical investigation of CYNK-001 in patients with GBM is expected to be the first clinical trial in the U.S. to investigate intratumoral administration of an allogeneic NK cell therapy ... WebCYNK-001 is the only cryopreserved allogeneic, off-the-shelf NK cell therapy developed from placental hematopoietic stem cells. CYNK-001 is being investigated as a potential treatment option in adults with COVID-19, as well as for …
Cynk-001 clinical trial
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Webestimated completion June 2024 Description Summary This study is a Phase 1 / 2 trial to determine the safety and efficacy of CYNK-001, an immunotherapy containing Natural Killer (NK) cells derived from human placental CD34+ cells and culture-expanded, in patients with moderate COVID-19 disease. Official Title WebCYNK-001 demonstrates a range of biological activities expected of NK cells, it can recognize and kill the stressed and/or virus-infected cells. With demonstrated safety data from in vivo and clinical study, it is concluded that CYNK-001 is the potential cellular therapy for COVID-19 treatment. Unmet Medical Need
WebFeb 1, 2024 · Experimental: Phase IIa Surgical rGBM CYNK-001 at MPD IV and IC. To evaluate efficacy and safety of CYNK-001 administrations in recurrent GBM at maximum … WebAug 5, 2024 · The first co-primary endpoint is to determine the virologic efficacy of CYNK-001 in facilitating the clearance of SARS-CoV-2 from mucosal specimens and/or peripheral blood. The second co-primary endpoint is to assess the impact of treatment with CYNK-001 on clinical symptoms among patients with COVID-19 related lower respiratory tract …
WebJun 2, 2024 · Background: CYNK-001 is a CD56+CD3- enriched, off-the-shelf, allogeneic natural killer (NK) cell product expanded from placental CD34 cells. CYNK-001 exhibits in vitro cytotoxicity against patient-derived GBM cell lines and secretes cytolytic cytokines during co-culture with cancer cells. WebApr 22, 2024 · Male Patients must agree to use a condom during sexual contact for at least 28 days following the last infusion of CYNK-001, even if he has undergone a successful vasectomy. ... Clinical Trials on CYNK-001. NCT05218408 Withdrawn . CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type …
WebSep 8, 2024 · The trial will evaluate the safety and clinical efficacy of CYNK-001 in SARS-CoV-2 positive subjects as measured by clearance of the SARS-CoV-2 and improvement in clinical symptoms or improvement ...
WebMar 31, 2024 · CYNK-001 is currently being investigated in two Phase 1 clinical trials, in AML and in GBM. In March 2024, the FDA granted Fast Track designation to CYNK-001 for the treatment of adults... iphone 14 pro max case with strapWebAug 11, 2024 · CYNK-001 has the potential to inhibit viral infection by killing host cells through indirect immune responses. CYNK-001 expresses NKG2D and DNAM-1 receptors in addition to cytotoxicity receptors NKp30, NKp44, and NKp46. ... Clinical Trials Clinical Trials . Phase Status Purpose Conditions Count; 1: iphone 14 pro max case with ringWebJul 1, 2024 · Background CYNK-001 is a cryopreserved, allogeneic, off-the-shelf natural killer (NK) cell investigational product derived from placental CD34+ cells. CYNK-001 … iphone 14 pro max charger boxWebDec 1, 2024 · CYNK-001 is an investigational cryopreserved allogeneic, off-the-shelf NK cell therapy developed from placental hematopoietic stem cells. CYNK-001 is being investigated as a potential treatment... iphone 14 pro max case with standWebJul 30, 2024 · View Clinical Trials for cynk-001. Cynk-001 has been investigated in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial investigating cynk-001, 1 is phase 1 (1 open). Drug Details. Synonyms : taniraleucel, human placental hsc-derived cd56+/cd3- nks cynk-001, cynk001, cynk 001, cd56+/cd3- nk cells cynk-001 (sy); … iphone 14 pro max case with pop socketWebMar 31, 2024 · Early price projections put CYNK-001 at between $2,000 and $7,000 per dose, and in the clinical trial, each patient will receive three doses over the course of one … iphone 14 pro max charger caseWebThis study will find the maximum tolerated dose or the maximum planned dose of CYNK-001 which contains natural killer (NK) cells derived from human placental CD34+ cells and culture-expanded. CYNK-001 cells will be given after lymphodepleting chemotherapy. The safety of this treatment will be evaluated, and researchers want to learn if NK cells ... iphone 14 pro max charger wireless